Amazon recently dropped the official trailer for Invincible season 2 part 2, and viewers are convinced they have spotted the Viltrumite Anissa. While the season does seem to be building up to her arrival, the show will need to be very careful how it adapts her storyline.
So far, Anissa has not been confirmed to be appearing in Invincible season 2. However, if the series follows the comic books, her arrival is inevitable. The first part of season 2 ended with quite a surprising twist. Mark (Steven Yeun) discovered his father, Omni-Man (J. K. Simmons), built a new life for himself on Thraxa, marrying a Thraxan and giving birth to another son. Unfortunately, the Viltrumites soon land on Thraxa and defeat Mark and Omni-Man. While Omni-Man is taken back to Viltrum, Mark is allowed to return to Earth. The only catch is that the Viltrumites expect him to complete the mission that Omni-Man failed and prepare Earth to become part of the Viltrumite empire.